Review



nrf2 specific inhibitor ml385  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 99
      Buy from Supplier

    Structured Review

    MedChemExpress nrf2 specific inhibitor ml385
    Nrf2 Specific Inhibitor Ml385, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 684 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nrf2 specific inhibitor ml385/product/MedChemExpress
    Average 99 stars, based on 684 article reviews
    nrf2 specific inhibitor ml385 - by Bioz Stars, 2026-02
    99/100 stars

    Images



    Similar Products

    nrf2 specific inhibitor ml385  (MedChemExpress)
    99
    MedChemExpress nrf2 specific inhibitor ml385
    Nrf2 Specific Inhibitor Ml385, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nrf2 specific inhibitor ml385/product/MedChemExpress
    Average 99 stars, based on 1 article reviews
    nrf2 specific inhibitor ml385 - by Bioz Stars, 2026-02
    99/100 stars
    		  Buy from Supplier
    nrf2 specific inhibitor ml385  (TargetMol)
    95
    TargetMol nrf2 specific inhibitor ml385
    Nrf2 Specific Inhibitor Ml385, supplied by TargetMol, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nrf2 specific inhibitor ml385/product/TargetMol
    Average 95 stars, based on 1 article reviews
    nrf2 specific inhibitor ml385 - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    nrf2-specific inhibitor ml385  (Aobious Inc)
    90
    Aobious Inc nrf2-specific inhibitor ml385
    Nrf2 Specific Inhibitor Ml385, supplied by Aobious Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nrf2-specific inhibitor ml385/product/Aobious Inc
    Average 90 stars, based on 1 article reviews
    nrf2-specific inhibitor ml385 - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    nrf2 specific inhibitor ml385  (Macklin Inc)
    90
    Macklin Inc nrf2 specific inhibitor ml385
    Nrf2 Specific Inhibitor Ml385, supplied by Macklin Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nrf2 specific inhibitor ml385/product/Macklin Inc
    Average 90 stars, based on 1 article reviews
    nrf2 specific inhibitor ml385 - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    nrf2 specific inhibitor ml385  (Selleck Chemicals)
    96
    Selleck Chemicals nrf2 specific inhibitor ml385
    Fig. 8. <t>ML385</t> eliminated the protective effects of notoginsenoside R1 in HAMI rats myocardial damage. (A) Myocardial injury was assessed by H&E staining (n=4). Blue arrow represents break-up of myocardial fibers; black arrow represents myocardial hemorrhage; and the green arrow represents inflammatory cells. Original magnification: ×20 (upper row); ×40 (lower row). Bar = 50 µm. (B) Ttransmission electron microscopy was applied to visualize changes in the organelles in cardiomyocytes (CMF, cardiac muscle fibers; Mi, mitochondria). Blue arrow represents break-up of myocardial fibers; red arrow represents mitochondrial changes of ferroptosis; and the yellow arrow represents expanded endoplasmic reticulum. Original magnification: ×12,000. Bar = 1 µm.
    Nrf2 Specific Inhibitor Ml385, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nrf2 specific inhibitor ml385/product/Selleck Chemicals
    Average 96 stars, based on 1 article reviews
    nrf2 specific inhibitor ml385 - by Bioz Stars, 2026-02
    96/100 stars
    		  Buy from Supplier
    nrf2  (MedChemExpress)
    99
    MedChemExpress nrf2
    Fig. 8. <t>ML385</t> eliminated the protective effects of notoginsenoside R1 in HAMI rats myocardial damage. (A) Myocardial injury was assessed by H&E staining (n=4). Blue arrow represents break-up of myocardial fibers; black arrow represents myocardial hemorrhage; and the green arrow represents inflammatory cells. Original magnification: ×20 (upper row); ×40 (lower row). Bar = 50 µm. (B) Ttransmission electron microscopy was applied to visualize changes in the organelles in cardiomyocytes (CMF, cardiac muscle fibers; Mi, mitochondria). Blue arrow represents break-up of myocardial fibers; red arrow represents mitochondrial changes of ferroptosis; and the yellow arrow represents expanded endoplasmic reticulum. Original magnification: ×12,000. Bar = 1 µm.
    Nrf2, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nrf2/product/MedChemExpress
    Average 99 stars, based on 1 article reviews
    nrf2 - by Bioz Stars, 2026-02
    99/100 stars
    		  Buy from Supplier

    Image Search Results


    Fig. 8. ML385 eliminated the protective effects of notoginsenoside R1 in HAMI rats myocardial damage. (A) Myocardial injury was assessed by H&E staining (n=4). Blue arrow represents break-up of myocardial fibers; black arrow represents myocardial hemorrhage; and the green arrow represents inflammatory cells. Original magnification: ×20 (upper row); ×40 (lower row). Bar = 50 µm. (B) Ttransmission electron microscopy was applied to visualize changes in the organelles in cardiomyocytes (CMF, cardiac muscle fibers; Mi, mitochondria). Blue arrow represents break-up of myocardial fibers; red arrow represents mitochondrial changes of ferroptosis; and the yellow arrow represents expanded endoplasmic reticulum. Original magnification: ×12,000. Bar = 1 µm.

    Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    Article Title: Notoginsenoside R1 treatment facilitated Nrf2 nuclear translocation to suppress ferroptosis via Keap1/Nrf2 signaling pathway to alleviated high-altitude myocardial injury.

    doi: 10.1016/j.biopha.2024.116793

    Figure Lengend Snippet: Fig. 8. ML385 eliminated the protective effects of notoginsenoside R1 in HAMI rats myocardial damage. (A) Myocardial injury was assessed by H&E staining (n=4). Blue arrow represents break-up of myocardial fibers; black arrow represents myocardial hemorrhage; and the green arrow represents inflammatory cells. Original magnification: ×20 (upper row); ×40 (lower row). Bar = 50 µm. (B) Ttransmission electron microscopy was applied to visualize changes in the organelles in cardiomyocytes (CMF, cardiac muscle fibers; Mi, mitochondria). Blue arrow represents break-up of myocardial fibers; red arrow represents mitochondrial changes of ferroptosis; and the yellow arrow represents expanded endoplasmic reticulum. Original magnification: ×12,000. Bar = 1 µm.

    Article Snippet: Dexamethasone (#S1322) and the Nrf2-specific inhibitor ML385 (#S8790) were obtained from Selleck Chemicals (Houston, TX, USA).

    Techniques: Staining, Electron Microscopy

    Fig. 9. ML385 eliminated the anti-ferroptosis of notoginsenoside R1 in HAMI rats myocardial damage. (A) Western blotting analysis of Keap1, GPX4, SLC7A11, FTH1, HO-1, and TFRC. (B) Effect of ML385 on Nrf2 localization in the nucleus and cytoplasm through Western blotting analysis. (C) Impacts of notoginsenoside R1 on GPX4 and Nrf2 levels was investigated using immunofluorescence staining. Red arrow represents nuclear translocation of Nrf2. Original magnification: ×20. Bar = 50 µm. The values are expressed as the means ± SEM (n = 7). ##P < 0.01, ###P < 0.001, and ####P < 0.0001 versus the HHM group; @@@P < 0.001 and @@@@P < 0.0001 versus the NR1 100 group.

    Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    Article Title: Notoginsenoside R1 treatment facilitated Nrf2 nuclear translocation to suppress ferroptosis via Keap1/Nrf2 signaling pathway to alleviated high-altitude myocardial injury.

    doi: 10.1016/j.biopha.2024.116793

    Figure Lengend Snippet: Fig. 9. ML385 eliminated the anti-ferroptosis of notoginsenoside R1 in HAMI rats myocardial damage. (A) Western blotting analysis of Keap1, GPX4, SLC7A11, FTH1, HO-1, and TFRC. (B) Effect of ML385 on Nrf2 localization in the nucleus and cytoplasm through Western blotting analysis. (C) Impacts of notoginsenoside R1 on GPX4 and Nrf2 levels was investigated using immunofluorescence staining. Red arrow represents nuclear translocation of Nrf2. Original magnification: ×20. Bar = 50 µm. The values are expressed as the means ± SEM (n = 7). ##P < 0.01, ###P < 0.001, and ####P < 0.0001 versus the HHM group; @@@P < 0.001 and @@@@P < 0.0001 versus the NR1 100 group.

    Article Snippet: Dexamethasone (#S1322) and the Nrf2-specific inhibitor ML385 (#S8790) were obtained from Selleck Chemicals (Houston, TX, USA).

    Techniques: Western Blot, Immunofluorescence, Staining, Translocation Assay